AJAYI
Adesuyi
EDUCATIONAL QUALIFICATION:
B.Sc. MB.ch.B. Ph.D, ECFMG, FWACP, FBPharmacols
LICENSURE:
– Nigeria Medical Council, Full registration, 1981;
– General Medical Council of Great Britain, limited,1991;
– South Carolina Board of Medical Examiners, 1993(LL 25150);
- Married
Adjunct Professor of Medicine, Baylor College of Medicine, Department of Medicine, Division of Hypertension and Clinical Pharmacology, Houston , TX 77060, 2001 till date; Editorial board, Current Diabetes Reviews, 2004 till date; Editorial Board, The Open Journal of Heart Failure, 2008 till date;
ACADEMIC AND RESEARCH POSITIONS
– Lecturer I, University of Ife, Ile-Ife, 1985-1987;
– Senior Lecturer, Department of Medicine, Obafemi Awolowo University, 1987-1989;
– Reader in Medicine, Obafemi Awolowo University, Ile-Ife, Nigeria 1989-1992;
– Professor of Medicine, Obafemi Awolowo University, Ile-Ife, Nigeria , 1992-2000;
– Public Enlightenment on Radio ( Osun State Radio) and TV ( NTA – IBADAN ) on Hypertension and Heart Failure, Diabetes Treatment and Control, 1995-1996;
– Anatomy Demonstrator (part time Instructor ) Department of Anatomy and Cell Biology, University of Ife, Ile –ife, 1977-1979;
– Rotating Intern, Registrar and Fellow in Internal Medicine & Cardiology, and Acute care, 1980-1982, 1985-1989;
– Vice-Dean , Faculty of Clinical Sciences (Medical School) Obafemi Awolowo University, 1994-1995;
– Professor and Chair of Medicine, Obafemi Awolowo University Medical School
Ile-Ife, Osun state, 1992-2000;
– Senior Scientist and Visiting Professor, Center for Cardiovascular Diseases, Texas Southern University, 3100 Cleburne Avenue, Houston ( NIH supported). Head of the Hypertension Subsection. Supervision of interns and post-doctoral researchers, Texas, 77004. USA, 1999-2004;
– Professor of Pharmacology and Clinical Therapeutics, St Matthew’s University School of Medicine, PO Box 32330 SMB, Safehaven, Grand Cayman Islands, BWI, 2005;
– Consulting Author in Pharmacology , USMLEWORLD . LLC, March -October 2005;
– Professor of Pharmacology, Ross University School of Medicine, PO Box 266, Roseau Common Wealth of Dominica, 2006;
– Professor of Biomedical Sciences, Department of Health Studies, College of Health Sciences, Chicago State University, 9501 S King Drive, Chicago IL 60628. 2007-2008;
– Professor of Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Chicago State University, 9501 S King Drive, Chicago IL 60628.(Part of Founding Faculty Professor. Program now accredited). 2008 to 2012;
– Professor of Pharmacology, St James School of Medicine, Anguilla , BWI, 2012-2013;
– Professor of Pharmacology, Saba University School of Medicine, the Bottom. Saba Dutch Caribbean, 2013-2014;
CLINICAL PRACTICE HOSPITAL ROLES
– Consultant Physician, Clinical Pharmacologist and Cardiologist, 1989- 1999;
– Member, Hospital Drug Revolving Fund Committee;
– Member, Hospital and University Research and Ethics Committee of OAUTHC Hospitals;
OTHER ADMINISTRATIVE DUTIES AT CHICAGO STATE UNIVERSITY
– Member, University Faculty Senate, Chicago State University;
– Member, University Personnel Committee, Chicago State University;
– Member, Departmental Personnel Committee, Dept of Pharmaceutical Sciences;
– Chicago State University Institutional Review Board -2010-2012.
EXTERNAL EXAMINERSHIPS
– University of Nigeria, Faculty of Medicine, Pharmacology & Therapeutics 1989-1991;
– Course Coordinator in Cardiology, West African College of Physicians,1990-1992;
– University of Ibadan, Faculty of Medicine- Pharmacology & Therapeutics 1996-1998;
– University of Benin, Faculty of Medicine- Department of Medicine, 1998;
EDITORIAL REVIEW FUNCTION
– Editorial board member, West African Journal of Pharmacology, 1990-1995;
– Reviewer, Journal of Hypertension, African Journal of Medicine and Medical Sciences. American Journal of Cardiovascular Drugs, Ethnicity and Disease.
Journal of the National Medical Association, 1991-2001;
– Reviewer, American Journal of Cardiovascular Drugs, 2001;
– Reviewer, Clinical Pharmacology & Therapeutics- 2001;
– Reviewer, The Wellcome Trust Grants UK, 2002;
– Reviewer, Diabetic Medicine, 2002;
– Reviewer, Diabetic Medicine, 2003;
– Reviewer, Pharmacology, Biochemistry & Behavior, 2004;
– Borno Medical Journal-Editorial board, 2004;
– Reviewer, Journal of pharmacy and pharmacology, 2006;
– Reviewer, Journal of Infectious Disease, 2006;
– Reviewer, Malaria journal (France), 2007;
– Reviewer, Gender Medicine, 2007-2008;
– Reviewer, Archives of Drug Information, 2007-2009;
– Reviewer, Journal of Sexual Medicine, 2009;
– Reviewer, American Journal of Nephrology, 2009;
– Reviewer, Diabetic Medicine, 2009;
– Reviewer, Case studies in Medicine, 2009;
– Reviewer, Journal of Cardiovascular Pharmacology, 2006-2010;
– Reviewer, Platelets, 2010;
– Reviewer – International Journal of Cardiology, 2006-2011;
– Reviewer, Circulation, 2006-2011;
– Reviewer, CardioVascular Journal of Africa, 2016-2017;
– Editorial Board Member, Journal of Pharmacology and Clinical Research, 2017;
– Reviewer, Diabetes, Obesity and Metabolism, 2018.
MEMBERSHIP OF PROFESSIONAL BODIES:
– Member, Nigerian Medical Association, 1980;
– Member, Glasgow Clinical Pharmacology Group, 1982;
– Member, New York Academy of Science, 1984;
– Member, British Pharmacological Society, 1986;
– Member, Nigerian Cardiac Society, 1989;
– Member, Association of Hospital Consultants, 1989;
– Member, West African Society for Pharmacology, 1990;
– Member, American Society for Clinical Pharmacology and Therapeutics, 1993;
– Member, American Federation for Clinical Research (Complimentary membership), 1994;
– Member, American Association for the Advancement of Science, 1994;
– Member, Nigerian Hypertension Society, 1995;
– Member, American Physiological Society, 2000;
– Member, Great Ife Alumni Association (USA), 2000;
– Member, Houston Local Authors Society, 2001;
– Member, International Society of Hypertension in Blacks (ISHIB), 2001;
– Member, American Diabetic Association, 2002;
– Member, EuroMD Net organization, ( network of physicians , physician –scientists, industry), 2006;
– Member, Index Copernicus, (Invited Membership to impactful researchers in the sciences), 2006
AWARDS AND DISTINCTIONS
– Recipient, University Scholar ”, University of Ife, Ile-Ife, Nigeria. (Designation and Award to best students with First class grade performance), 1975;
– Recipient, Ondo State, Nigeria Post –Secondary Merit Award ( First set awarded), 1976;
– Recipient, Foundation Dean Medalist- Undergraduate Best Student Prize, Faculty of Medicine, University of Ife, Ile-Ife, Nigeria, 1977;
– Recipient, Faculty Prize, Overall best student in the Faculty of Medicine, 1977;
– Recipient, First Prize Cup/First Position by Nigerian Medical Students Association Intermedical School Quiz Competitions, 1979-1980;
– University of Glasgow Postgraduate Scholar ( Faculty of Medicine), 1982;
– Committee of Vice-Chancellors and Principals of UK universities Award (ORS).
( For Overseas Students of outstanding academic merit and research potential), 1982;
– Recipient, Federal Government of Nigeria Postgraduate Scholarship , 1983;
– Wellcome Trust Clinical Research Fellowship, 1991;
– Merck,Sharp & Dohme International Fellow in Clinical pharmacology, 1992;
– Recipient, Young Investigator Award for Excellence in Scientific research. Baltimore , Maryland by American Society for Clinical Investigation/American Federation For Clinical Research, 1994;
– Recipient, First Alumni Professor of Medicine Award & Feschrift- Ife University Medical Students Association, 1995;
– Recipient, The Outstanding Young Person of Nigeria Award, for Academic accomplishments and leadership. ( Junior Chamber International), 1996;
-Biographee, Marquis Who-is-Who in the World. 16th Edition, 1999;
– Recipient, Distinguished Alumnus Award by Obafemi Awolowo University, Ile-Ife, Nigeria, 2002;
– Biographee, Who-is-Who in Nigeria, Nigerian Biographical institute, 2003;
– Invited Symposium speaker, “ Non genomic effects of estrogens”. –American Society of Pharmacology and Experimental Therapeutics-FASEB. San Diego, CA, 2003;
– Recipient, International Order of Merit (IOM) –International Biographical Center, Cambridge, England, UK [ Membership restricted to 500 in the World at any time]For services to clinical pharmacology and the human society, 2005;
– Fellow, British Pharmacological Society (FBPharmacolS) – Election to Fellowship based on distinction in pharmacology and contribution to the Society, 2006;
–
PUBLICATIONS
CURRENT RESEARCH
– The interaction of sex-hormones , hyperinsulinemia and paracrine autocoids in the progression of type-2 diabetic endotheliopathy in Zucker diabetic rats;
– The influence of ethnicity and hemoglobin AS trait on platelet and microvascular reactivity and on the target organ complications of type-2 diabetic patients using doppler –laser flowmetry;
– Cross-talk among the heptahelical G-protein coupled receptors in health and disease.
– The role of angiotensin II receptor subtypes and nitric oxide synthase isoforms in the development of cardiac cachexia in experimental and clinical heart failure;
– Determination of the chemistry of an African aphrodisiac penile erection enhancer, [ Burantashi ]with alpha-2 antagonist, endothelin –1 and nitric oxide actions;
– Hyperglycemia – Protein Kinase C connections – the physiological and pathological role of androgen receptor in diabetic microvascular disease. The use of telemedicine for intervention in Metabolic –syndrome (Met S) prevention and advancement to the “deadly quartet”;
– The role of matrix metalloproteinases in valvular regurgitation and left ventricular remodeling in hypertensive heart disease;
– Combined Renin –Angiotensin-System Blockers Effects , Beta blockers on the Cardiac remodeling in Hypertensive heart disease and Failure;
– Development of algorithm of biomarkers and intervention for the prophylaxis of Sudden cardiac deaths;
– Biomarkers in drug development and targets for drug efficacy.
THESIS/DISSERTATION
– “Studies on Somato-Visceral Reflexes in the rat.” B.Sc (Health Sciences), 1977;
– “Typhoid Enteropathy in Ile-Ife in 1980” – Final M.B. Ch. B Community Medicine Dissertation, 1980;
– Clinical and Pharmacological Studies on Angiotensin- I Converting Enzyme Inhibitors”, Ph.D. Thesis, 1985;
– Enalapril in hypertension and heart failure in Nigerians”, Final F.W.A.C.P. Dissertation, 1989.
BOOKS/MONOGRAPH
AUTHORED BOOKS
– A. A. Ajayi., A Handbook of Rapid Bedside Physical Examination and Pathophysiology College Press (Ltd.) Ibadan, ISBN 978-2194-05-0, 1995;
– A.A Ajayi., Angiotensin converting enzyme inhibition in Nigerians, 1997;
– A.A. Ajayi., Diaspora Medicine. ISBN-0-971043-0-1-2001, reprinted 2013;
– Adesuyi A L Ajayi & Abimbola T Ajayi., Immigration and Health published by Authorhouse Inc ISBN 978-1-4343-9129-2, 2008;
– E-Book Version, Immigration and health USA by Smashword, 2012.
EDITED BOOKS
– “Cardiology: Review and Update”- Ajayi A.A. editor, West African College of Physicians, Lagos, 1990;
– “Cardiology” R.O. A. Makanjuola & A.A. Ajayi ed., Shaneson Press Ltd., Ibadan, ISBN 978-240-041, 1993.
CONTRIBUTIONS TO BOOKS
– A.A. Ajayi et al. “Androgen regulation of thromboxane A2 recptors: In, Advances in Prostaglandins, Thromboxanes and Leukotriene Research, 251-253, Vol 21, Raven Press, New York, Ed. Samuelsson B. et al., 1994;
– Ajayi AA. “Hypertension- Treating patients, not just pressures” Chapter 7. Cardiology 1993 Makanjuola RO & Ajayi (editors) Shaneson press Ltd. Ibadan;
– Ajayi AA. “Vasodilators, Intropes and thrymbolytic agents” Chapter 9. Cardiology 1993. Makanjuola RO & Ajayi (editors) Shaneson press Ltd. Ibadan;
-Ajayi AA “Clinical Pharmacology in the treatment of cardiac disease” Cardiology Review and Update- Ajayi AA (Editor) West African College of Physicians, Lagos, 1990;
– Sofowora GG, Ajayi AL. Medical Treatment of Heart Failure . 1.
TECHNICAL REPORTS
– The effect of age on the pharmacokinetics and pharmacodynamics on ACEI enalapril, enalaprilat., Submitted to Merck co . Rahway , NJ. USA;
-The effect of S-9490-3 on autonomic function in healthy volunteers – Servier , France;
– Pharmacodynamics, dose response relationships, and autonomic function after cilazapril. – submitted to Hoffman la Roche. Basel, Switzerland;
– The effect of naloxone on the actions of captopril . Prepublication report sent to Dupont Chemicals, NJ . USA;
– The effect of lacidipine in hypertensive Nigerians, submitted to Glaxo Smith Kline;
– Comparison of cilazapril, hydrochlothiazide and their combination in hypertensive Nigerians. Hoffman la Roche, Basel Switzerland.
PUBLISHED PEER REVIEWED JOURNAL ARTICLES
– Ajayi AA. Campbell, B.C., Howie, C.A.,Reid, J.L : Acute and chronic effects of angiotensin converting enzyme inhibitors, enalapril and lisinopril on the reflex control of heart rate in normotensive man. Journal of Hypertension, 3, 47-53, 1985;
– Ajayi A.A., Campbell B.C. Meredith P.A., Kelman, A.W. And Reid J.L. : The effect of captopril on reflex control of heart rate: Possible mechanisms. British Journal of Clinical Pharmacology, 20, 17-25, 1985;
– Ajayi A.A., Campbell B.C, Howie C.A., Kelman, A.W., Meredith P.A. And Reid J.L. The pharmacodynamics and population pharmacokinetics of enalapril and lisinopril. International Journal of Clinical Pharmacological Research, V (6), 419-427, 1985;
– Andy J.J., Ladipo G.O.A., Owolabi S.P., Teniola S.O., Ajayi A.A., Akinola N.O and Morakinyo O. Blood pressure distribution of Nigerians in the first two decades of life. Annal of Tropical Pediatrics, 5, 113-118, 1985;
– Ajayi A.A., Campbell B.C., Rubin P.C., and Reid J.L., Effect of naloxone on the actions of captopril. Clinical Pharmacology and Therapeutics, 38, 560-565, 1985;
– Ajayi A.A., and Reid J.L., The effect of enalapril on baroreceptor mediated reflex function in normotensive subjects. British Journal Clinical Pharmacology, 21, 338-339, 1996;
– Hockings N. Ajayi A.A. and Reid J.L., Age and the pharmacokinetics of angiotensin converting enzyme inhibitors, enalapril and enalaprilat. British Journal of Clinical Pharmacology, 21, 341-348, 1986;
– Ajayi A.A., Hocking N. and Reid J.L., Age the pharmarcodynamics of angiotensin converting enzyme inhibitors, enalapril and enalaprilat. British Journal of Clinical Pharmacology, 21, 349-357, 1986;
– Ajayi A.A., Lees K.R. and Reid J.L., Effects of angiotensin converting enzyme inhibitor, perindopril on autonomic reflexes, European Journal of Clinical Pharmacology, 30, 177-182, 1986;
– Ajayi A.A, Rubin P.C. and Reid J.L., Captopril and opiate antagonism in essential hypertension. British Journal of Clinical Pharmacology, 21, 543-545, 1986;
– Ajayi A.A., Elliot H.L. Reid J.L., The pharmacodynamics and dose-response relationships of angiotensin converting enzyme inhibitor, cilazapril in essential hypertension. British Journal of Clinical Pharmacology, 22, 167-175, 1986;
– Ajayi A.A., Hocking N., and Reid J.L., The relationship between serum enalaprilat concentrations the hypotensive effect in man. International Journal of Clinical Pharmacology Research, 7(1) 1-3, 1987;
– Ajayi A.A., and Reid J.L., Renin, Angiotensin- modulation of sympathetic reflex function in essential hypertension and in the elderly. International Journal of Clinical Pharmacology Research, 8(5) 327-333, 1988;
– Ajayi A.A., Parasympathetic cardiac activity: Differential effects of aging and hypertension, East African Medical Journal, 65(8), 520-524,1988;
– Balogun M.O., Ajayi A.A., Ladipo G.O.A., Spectrum of treadmill exercise responses in Africans with normotensive, essential hypertension and hypertensive heart failure. International Journal of Cardiology, 21 (3), 293-300, 1988;
– Ajayi A.A. Balogun M.O. Oyewo E.A. Ladipo G.O.A., Enalapril in African patients with congestive cardiac failure. British Journal of Clinical Pharmacology, 27, 400-403, 1989;
– Ajayi A.A., Oyewo E.A. Ladipo G.O.A. and Akinsola A., Enalapril and hydrochlorothiazide in hypertensive Africans. European Journal of Clinical Pharmacology, 36, 229-234, 1989;
– Ajayi A.A. and Reid J.L, Cardiovascular and endocrine effects of cilazapril, a new ACE-inhibitor in man. African Journal of Medicine and Medical Sciences, (1) 33-38, 1989;
– Ajayi A.A, Oluokun A.R., Sofowora O, Akinleye A, Ajayi A.T., Epidemiology of anitmalarial-induced pruritus in Africans. European Journal of Clinical Pharmacology, 37(5), 539-540, 1989;
– Elliot H.L., Ajayi A.A., Reid J.L., The influence of cilazapril on indices of autonomic function in normotensives and hypertensives. British Journal of Clinical Pharmacology, 27,303s-307s, 1989;
– Oyewo E.A., Ajayi A.A., and Ladipo G.O.A., A therapeutic audit in the management of hypertension in Nigerians. East African Medical Journal, 66(7), 458-467, 1989;
– Ajayi A.A., Balogun M.O., Ajayi A.T., Correlation among radiologic, echocardiographic indices and self-paced exercises capacity in heart failure. International Journal of Cardiology, 27(1), 136-137, 1990;
– Ajayi A.A., and Ajayi A.T., Angiotensin converting enzyme inhibition reduces proteinuria in Nigerians with chronic renal disease. European Journal of Clinical Pharmacology, 39(4), 423-424, 1990;
– Ajayi A.A., Balogun M.O., Sustained beneficial effects of enalapril in Africans with congestive heart failure. International Journal of Cardiology, (1), 55-61, 1990;
– Adamolekun B., Ajayi A.A., Primary writing tremor in a Nigerian: Role of tremorogenic beta-adrenoceptors. Nigerian Medical Practitioner, 20(4), 83-86, 1990;
– Ajayi A.A. Angiotensin converting enzyme inhibitors in cardiovascular and renal disease in Africans: A review. African Journal of Medicine & Medical Sciences, 20, 123-134, 1991;
– Ajayi A.A., Estimation of creatinine clearance: Utility of the Cockcroft and Gault equation in Nigerian patients. European Journal of Clinical Pharmacology, 40,429-431, 1991;
– Ajayi A.A. and Babalola R.O., Enalapril and hydrochlorothiazide combination in hypertensive-diabetic Africans with proteinuria. International (Practical) Diabetes Digest, 2(2), 51-52, 1991;
– Ajayi A.A. Akinleye A.O., Udoh S.J., Ajayi O.O., Oyelese O., Ijaware C., The effect of Predinsolone and Niacin on Chloroquine-induced pruritus in malaria. European Journal of Clinical Pharmacology, 41, 383-385, 1991;
– Ajayi A.A., and Balogun J.A., Symptom-linked, self-paced walking in the assessment of cardiovascular disease: predictive value of echocardiographic, clinical and ergonometric parameters. International Journal of Cardiology, 33, 233-240, 1991;
– Balogun J.A., Isi J., and Ajayi AA., Cardiovascular effects of the inversion of the head. Journal of Physiotherapy Science, 4, 1-11, 1992;
– Ajayi A.A., Akinsola A., Ajayi A.T. and Sanusi O, Problem of follow-up of renal transplant recipients in the tropics. Trop & Geogr. Med., 44(2), 170-173, 1992;
– Babalola R.O. and Ajayi A.A., A cross-sectional study of echocardiographic indices, treadmill exercise capacity and microvascular complications in hypertensive diabetic Nigerians. Diabetic Medicine, 9, 809-903, 1992;
– Ajayi A.A., Oshodi O., Akintomide A.O. : The influence of captopril on intrahospital mortality and duration of hospitalization in Nigerians with congestive heart failure. International Journal of Cardiology, 36, 341-343, 1992;
– Ajayi A.A. and Akinwusi P.O., Spectrum of hypertensive heart disease in Nigerians: A cross-sectional study of echocardiograpbic indices and the correlation to treadmill exercise capacity. Journal of Hypertension, 11, 99-102, 1993;
– Durosinmi M.A. Ajayi A.A., A prospective study of Chloramphenicol- induced aplastic anemia in Nigerians. Trop. Geogr. Med., 45, 159-161, 1993;
– Balogun A., Oyeyemi O., Ajayi A.A., Effects of aerobic training on the cardiovascular response to head-down posture. J. Phys. Ther. Sci., 5,1-12, 1993;
– Ajayi A.A. and Ukponmwan O.E. Evidence of angiotensin-II and endogenous opioid modulation of novelty-induced rearing in the rat. African Journal of Medicine and Medical Sciences, 23, 287-290, 1994;
– Ajayi A.A., Akintomide A.O., Babalola R.O. and Akinwusi P.O., Disproportionate intraventricular septal hypertrophy in Nigerians with essential hypertension. African Journal of Medicine and Medical Sciences, 24,93-96, 1994;
– Ajayi A.A., Raji M.A., Acute cardiovascular effects of the concurrent administration of enalapril, amlodipine or prazosin in healthy Nigerians. International Journal of Cardiology, 44, 79-84, 1994;
– Ajayi A.A., Antiarrhythmic action of enalapril in congestive heart failure: Possible contribution of altered sympathovagal autonomic balance on the heart. Int. J. Cardiol., 47, 195-196, 1994;
– Ajayi A.A. Mathur R., Halushka P.V., Testosterone Increases human platelet thromboxane A2 receptor density and aggregation responses. Circulation, 91, 2742-2747, 1995;
– Ajayi A.A, Increase in plasma B-endorphins precedes vasodepressor syncope (Letter) Br. Heart Journal. 73(5), 488-488, 1995;
– Ajayi A.A Fox S.C., Rubin P.C., Allen B.R., A study of the possible role of the 12-lipogenase pathway in Chloroquine pruritus. Niger. Med. J. 1995, 29, 2, 78-79, 1995;
– Ajayi A.A., and Akintomide A.O. The efficacy and tolerability of amlodipine and hydrochlorothiazide in Nigerians with Essential hypertension. J. Natl. Med. Association, 87, 485-488, 1995;
– Oyelola O.O., Ajayi A.A., Stein R. and Babalola R.O., Lipids, Lipoprotein and apoprotein profiles in hypertensive, diabetic and hypertensive-diabetic Nigerians. J. National Medical Association, 87, 113-118, 1995;
– Ajayi A.A. Sofowora G.G., Balogun M.O., Clinical Implications of the inhibitions of the “cross-talk” between α-1 adrenoceptor blockade and converting enzyme inhibition in the treatment of heart failure. Afr. J. Med. & Med. Sci, 25,95, 1996;
– Ajayi A.A., Afolabi M.A., Balogun M.O., Adigun AQ, Akintomide AO., Oral therapy with combined enalapril, prazosin and hydrochlorothiazide in the acute treatment of severe hypertension in Nigerians. Eur. J. Clin Pharmacol, 51, 45-48, 1996;
– Ajayi A.A, Sofowora GG, Balogun M.O., Concurrent α-1 adrenergic blockade and ACE-inhibition in the treatment of congestive heart failure. International Journal of Cardiology, 57 173-176, 1996;
– Adewole A.D., Ikem R.T., Adigun A.Q., Akintomide A.O., Balogun M.O., Ajayi A.A.L, Three year review of the impact of ACE-inhibitiors on intra-hospital mortality of Nigerians with chronic heart failure, Central African Journal of Medicine, 42, 253-256, 1996;
– Ajayi A.A : Novel aspects of the molecular and clinical pharmacology of ACE-inhibition relevant to cardiovascular diseases Nigerian Medical . Journal ., 31,45-51(State –of the Art Lecture), 1996;
– Adebayo R., Sofowora G.G., Onayemi O, Udoh S.J. Ajayi A.A., Chloroquine-induced pruritus in malaria: Role of malaria parasitemia and the effects of Prednisolone, Niacin and the combination compared to anithistamines. Br. J. Clin. Pharmacol, 44, 157-161, 1997;
– Adigun A.Q. Ajayi AA. Accidental overdose with enalapril and prazosin. Nigeria Medical Practitioner, 34, 56-57, 1997;
– Ajayi A.A., Olotu T.C., Sofowora G.G., Knowledge attitude and practice of prednisolone prevention of chloroquine-induced pruritus among Nigerian Health Workers Tropical Doctor, 28(4), 210-211, 1998;
– Rotimi O. Ajayi A.A., Odesanmi W.O., Sudden unexpected death due to cardiac causes in Nigerians: A review of 50 autopsied series. Int J Cardiol , 63, 111-115, 1998;
– Sofowora GG, Adigun AQ, Haastrup AT, Ajayi AA., Evidence of synergism between ACE inhibitor and alpha-1 antagonist during Isometric handgrip in normal man. Cardiologie Tropicale- Tropical Cardiology, 25 (96) 111, 1998;
– Adigun AQ, Ajayi AA., Muscarinic blockade with Oral hyoscine palliates ACE-inhibitor induced cough, Afr J Med Med Sci., 27, 139, 1998;
– Kolawole BA, Ajayi AA., Prognostic indices for hospital mortality in hypertensive diabetic Nigerians. Diabetes International , 12(3) 77-81, 1998;
– Adigun AQ, Ajayi OE, Sofowora GG, Ajayi AA., Vasodilator therapy of hypertensive acute pulmonary edema. Comparison of captopril- prazosin and hydralazine- isosorbide dinitrate. International Journal of Cardiology, 67, 81-86, 1998;
– Olateju SO, Ajayi AA. Lack of efficacy of β- adrenergic-blockers .timolol and betaxolol on intraocular pressure in healthy Nigerians. Eye 1999. 13, 758-63. [ Rated Best paper of the year in the journal Eye , Journal of the Royal College of ophthalmologists];
– Ajayi AA, Adigun AQ, Ojofeitimi EO, Yusuph H, Ajayi OE. Anthropometric evaluation of cachexia in chronic congestive heart failure: role of tricuspid regurgitation. International Journal of Cardiology, 71, 79-84, 1999;
– Kolawole B, Ajayi AA., Prognostic Indices of intra-hospital mortality in hypertensive diabetic NIDDM Nigerians: Role of gender and hypertension. J Diabetes Complications, 14, 83-87, 2000;
– Onigbogi O. Ajayi AA. Ukponmwan OE. Chloroquine induced body scratching behavior in rats: evidence of involvement of endogenous opioid peptides. Pharmacology Biochemistry & Behavior, 65, 333-337, 2000;
– Sanusi AO, Akinsola A. Ajayi AA. Prediction of creatinine clearance from serum creatinine in Nigerians: A comparison of the predictive accuracy of five formulae. African Journal of Medicine & Medical Sciences,29, 163-167, 2000;
– Adigun AQ, Sofowora GG, Ajayi AA. Chronotropic atropine dose response in congestive heart failure; Assessment of interethnic variation and the reversibility of parasympathetic dysfunction. Ethnicity and Disease, 10, 203-207, 2000;
– Ajayi AA, Adigun AQ, Angiodema and cough in Nigerian patients receiving ACE inhibitors. British Journal of Clinical Pharmacology, 50, 81-82, 2000;
– Ajayi AA. Mechanisms of Chloroquine induced pruritus. Clin Pharmacol Ther, 68, (3) 336-7, 2000;
– Adigun AQ & Ajayi AA. The effect of enalapril-digoxin-diuretic combination on the nutritional and anthropometric indices in congestive heart failure: preliminary findings in cardiac cachexia. European Journal of Heart Failure, 3, 359-363, 2001;
– Adigun AQ & Ajayi AA A prospective study of ACE inhibitor- induced cough in Nigerians West African Journal of Medicine,20, 46-7, 2001;
– Ajayi AA, Hercule HC, Pamugo J, Dixon D, Oyekan AO. Interactions of the renin-angiotensin system and alpha-1 adrenoceptors on renal hemodynamics in healthy and acute renal failure rats. Blood Pressure, 10, 238-246, 2001;
– Hercule HC, Ajayi AA, Oyekan AO. Differential effects of U46619 on renal regional blood flow; Evidence for the involvement of endothelin-1. J Pharmacol Exp Ther, 299, 372-6, 2001;
– Adigun AQ, Asiyanbola B, Ajayi AA, Cardiac autonomic function in blacks with congestive heart failure: vagomimetic action, alteration in sympathovagal balance, and the effect of ACE inhibition on central and peripheral cardiac vagal tone.Cell Molecular Biology, 47, 1063-1067, 2001;
– Ajayi AA, Adigun AQ, Syncope after oral chloroquine administration in hypertensive patient controlled on amlodipine. Br J Clin Pharmacol, 53 , 404-5, 2002;
– Ajayi AA, Sofowora GG, Adigun AQ, Asiyanbola B., Adjunctive sympathoplegic therapy to ACE inhbition in blacks with congestive heart failure: A comparison of alpha-1 with beta-1 blockade on exercise tolerance and cardiac sympathovagal reflex activity. Ethnicity & Disease, 13 (1) 71-79, 2003;
– Ajayi AA, Sofowora GG, , Adigun AQ, Asiyanbola B., New treatments for blacks with heart failure : for the patient. Ethnicity & Disease, 13, 150, 2003;
– Ajayi AA., Hercule HC. Hayes BE. Oyekan AO., Gender differences in the vascular and platelet reactivity to TXA2 mimetic U46619 and to endothelial dependent vasodilation in Zucker fatty (hyperinsulinemic, hypertensive) diabetic rats. Diabetic Research and Clinical Practice, 59, 11-24, 2003;
– Ajayi AA, Newaz M, Saleh M, Hercule C, Bode C, Oyekan AO., Endothelin-1 like action of an aqueous extract of Pausinystalia yohimbie on renal medullary blood flow and blood pressure in Sprague- Dawley rats. Methods & Findings in Exp & Clin Pharmacol , 25, 817-822, 2003;
– Adigun AQ, Ishola DA, Akintomide AO, Ajayi AAL., Shifting trends in the pharmacological management of essential hypertension in a Nigerian tertiary hospital. : a real world evaluation of the cost-effectiveness, safety, efficacy rationality, of new and older antihypertensive agents. J Human Hypertension, 17, 85-277, 2003;
– Ajayi AAL., Recommendations for prevention, diagnosis and management of hypertension and cardiovascular risk factors in SubSaharan Africa. [Comments], Journal of Hypertension, 22, (5)1047, 2004;
– Ajayi AA, Ogungbade O, Hercule HC, Oyekan AO, Mutembei L., Altered endothelin-receptor subtype responsiveness and ET-1 –TXA2 receptor interaction in hypertensive –diabetic Zucker rats. Diabetes Research and Clinical Practice, 63 (3) 155-169, 2004;
– Ajayi AA., Kolawole BA Sickle cell trait and gender influence complications in Africans with type-2 diabetes. Eur J Intern Med, 15 (5) 312-5, 2004;
– Ajayi AA, Kolawole BA, Udoh SJ. A double-blind controlled study of the antipruritic efficacy of μ opiate receptor antagonist, naltrexone, and promethazine on chloroquine induced pruritus in malaria fever. Inter Dermatology, 43, 7-972, 2004;
– Ajayi AA, Ogungbade GO, Okorodudu AO., Sex hormone regulation of systemic vascular endothelial and renal microvascular reactivity in Zucker diabetic rats. Eur J Clin Invest, 34, (5) 349-57, 2004;
– Ajayi AA. Impact factor misleading, citing all references. J National Medical Association, 96, 1374, 2004;
– Ajayi AA., Gender influences the impact of sickle cell trait on Type-2 diabetes complications. Diabetic Medicine, 22 (7) 954, 2005;
– Ajayi AA, Halushka PV. Castration reduces human platelet TXA2 receptor density and aggregability. QJM, 98 ( 5) 349-56, 2005;
– Ajayi AA., Should Sickle cell trait be re-classified as a disease state? Eur J intern Med, 16 (6) 463, 2005;
– Ajayi AA, Fidelis P, The effect of flutamide on systemic and renal hemodynamics in Zucker diabetic rats : paradoxical renal vasodilator response to ET-1 and TXA2 receptor activation in female gender. J Cardiovasc Pharmacol, 48(5) 191-8, 2006;
– Ogunbodede EO, Fatusi OA, Akintomide A, Kolawole K, Ajayi A., Oral health status in a Population of Nigerian Diabetics. J Contemp Dental Pract, (6)4:075-084, 2006;
– Ajayi AA. Singh D., First line treatment with beta-blockers followed by adjuvant ACE-inhibitors after six months may be safe in older people with heart failure Evidenced-based Cardiovascular Medicine, 10, 21-3, 2006;
– Ajayi AA, Cooper J, Horn EH, Rubin PC., Comparison of the effects of unfractionated heparin and the low molecular weight heparins, dalteparin and enoxaparin on spontaneous platelet aggregation, and adenosine diphosphate activity in platelets during the third trimester of pregnancy. Methods & Find Experimental Clin Pharmacol, 29: 539-45, 2007;
– Ajayi OE, Akintomide AO, Adigun AQ, Ajayi AAL., Left ventricular diastolic function in hypertensive Nigerians ; effects of ACE Inhibitors, Calcium antagonists or their combination. Arch Drug Inf, 1.(1) : 29-34, 2008;
– Ajayi OE, Abiona TC, Balogun MO, Ajayi AAL . Valvular regurgitation impact on left ventricular 2 dimensional and Doppler echocardiographic indices in Nigerian patients with essential hypertension. J Natl Med Assoc,102 : 937-42, 2010;
– Ajayi OE, Ajayi AA. Valvular regurgitations may increase risk of arrhythmias in hypertensive heart failure in Nigerians . J Cardiovasc Med (Hagerstown ), 14(6) 453-60, 2013;
– Olateju SO, Ajayi AA., The effects of combigan on intra-ocular pressure in Nigerian healthy volunteers. Arch ophthalmology (submitted), 2014;
– Ajayi AA The beneficial parasympathetic cardiovascular actions of inhibitors of the Renin-Angiotensin –System . Current Clinical Pharmacology Reviews –invited reviews, 2014;
– Ajayi OE, Balogun MO, Abiodun G, Adebayo RA, Ogunyemi S, Akintomide AO, Bamikole J, Ajayi AA. Patterns of arrhythmias in Nigerians with congestive heart failure. Int J Gen Med, 8 ; 125- 130, 2015;
– Ajayi OE, Ajayi AAL . The correlation of echocardiographic indices with left atrial and ventricular arrhythmias by 24 hour EKG Holter monitoring in hypertensive heart disease and hypertensive heart failure in black West Africans. Journal of Preventive Cardiology, 4, 698-705, 2015;
– Sofowora GG, Ajayi AL . Treatment of Congestive heart failure in Nigerians. Book Chapter in Management of Heart Failure ; Medical. Volume 1. By Ragavendra Baliga & Garrie Haas. ( Springer ).Chapter 17, 2015 in press;
– Olamoyegun M, Kolawole BA, Ajayi AA . Impact of hydrochlorothiazide and Lisinopril- thiazide combination on Beta cell function and Insulin sensitivity in Nigerians with Essential hypertension. J Pharmacology and Pharmacotherapeutics, 8 (2) 68-73, 2017;
– Ajayi OA, Ajayi AA. Nano and microtechnology emerging impact on pharmacology and medical advances : prospects and challenges. J Pharmacol and Clin Research, 02. 555599, 2017;
– Ajayi AA . Itching, chloroquine and malaria : a review of recent molecular and neuroscience advances and its contribution to mechanisms and possible therapeutics of non –histaminergic chronic itch . International Journal of Dermatology, 57, 2018 in press;
SUBMITTED MANUSCRIPTS
– Ajayi AA . Evaluation and Meta-analysis of studies investigating the role of neurohormonal inhibition treatment and its impact on outcomes in hypertensive heart failure, 2018;
PUBLISHED CONFERENCE PROCEEDINGS AND ABSTRACTS
– Andy J.J. Ladipo G. Teniola S. Ajayi A.A. Akinola N.O. and Owolabi S.P., Blood pressure in 4,464 Nigerian children and young adults aged 1-20 years. Proceedings of the 12th Annual Meeting of the Nigerian Cardiac Society. Ile-Ife, P.19, 1983;
– Ajayi A.A. Campbell B.C., Howie C.A., Reid J.L., Acute and chronic effect of enalapril and MK 521, on reflex control of heart rate in normotensive subjects. Proceedings of the British Pharmacological Society (BPS), London, 1984. British Journal of Clinical Pharamcology, 17, 607-608p, 1984;
– Ajayi A.A., Campbell B.C., Kelman A.W. Howie C.A., Miller J.A. and Reid J.L., Enalapril and lisinopril: Pharmacodynamics and population pharmacokinetics. BPS Proceedings, Birmingham 1984 British Journal of Clinical Pharmacology, 18, 273-274p, 1984;
– Ajayi A.A. Campbell B.C., Meredith P.A., Reid J.L., Mechanisms of the parasympathetic activity of angiotensin converting enzyme inhibitor in man. Proceedings of the 9th International Union of Pharmacology Congress (IUPHAR) London, abstract 936, 1984;
– Hockings N., Ajayi A.A., Hughes D.M. Lees K.I.R. Reid J.L., The effect of age on the pharmacodynamic response to angiotensin converting enzyme inhibitors enalapril and enalaprilat. BPS Proceedings, Dundee, 1984. British Journal of Clinical Pharmacology, 19, 140-141p, 1985;
– Ajayi A.A., Campbell B.C., Rubin P.C. Reid J.L., Endogenous opioids and central actions of captopril in man? Proceedings of 2nd European Meeting of Hypertension, Milan, Italy, Abstract No.3, 1985;
– Lees K.R. Ajayi A.A. Reid J.L., Effect on blood pressure and renin-angiotensin system of S-9490-3, a new angiotensin converting enzyme inhibitor. Proceedings of 2nd European Meeting on hypertension. Milan, Italy, 1985. Abstract No. 298, 1985;
– Hockings N. Ajayi A.A Reid J.L., The effects of age on the pharmacokinetics and dynamics of angiotensin converting enzyme inhibitors, enalapril and enalaprilat. BPS Proceedings, Cardiff, 1985. British Journal of Clinical Pharmacology, 20,262p, 1985;
– Ajayi A.A., Campbell B., Gilbert L., Summer D.J. Rubin P.C. and Reid J.L., The actions of naloxone on the cardiovascular and autonomic effects on captopril in man. BPS Proceedings, Cardiff, 1985. British Journal of Clinical Pharmacology, 20.262p-263p, 1985;
– Ajayi A.A. Elliot H.L., Hughes D.M., McCulloch J., Reid J.L., Pharmacodynamics and dose response relationship of angiotensin converting enzyme inhibitor, cilazapril in essential hypertension. Proc of Joint Italian Pharmacological Society and BPS Meeting, Edinburgh, 1985. British Journal of Clinical Pharmacology, 21, 92p, 1986;
– Oyewo E.A., Ajayi A.A., Ladipo G.O.A., A therapeutic audit in the management of essential hypertension. Proceedings of 16th Annual meeting of the Nigerian Cardiac Society, Calabar, P. 19, 1987;
Ajayi A.A., Ladipo G.O.A., Oyewo E.A., Akinsola A., Enalapril an angiotensin converting enzyme in hypertensive Nigerians, proceedings of 12th Annual Scientific Meeting of the West African College of Physicians,Lagos, P.19, 1987;
– Ajayi A.A., Balogun M.O., Oyewo E.A. and Ladipo G.O.A., Angiotensin converting enzyme inhibition with enalapril in Nigerian patients with congestive heart failure. Proceedings of the 17th Annual Scientific Meeting of the Nigerian Cardiac Society, Ibadan, Abstract No. 14, 1988;
– Balogun M.O., Ajayi A.A. Ladipo G.O.A., Spectrum of exercise treadmill responses in normotension, essential hypertension and hypertensive heart failure. Proceedings of the 17th Annual Scienitic Meeting of the Nigerian Cardiac Society. Ibadan, Abstract No. 17, 1988;
– Ajayi A.A., Enalaprilat concentration effect modeling. 1st Intenational Symposium on Heart Failure. Mechanisms and Management, Jerusalem, Israel. Abstract Poster 109, 1989;
– Ajayi A.A., Balogun M.O., Oyewo E.A. and Ladipo G.O.A., Angiotensin converting enzyme inhibition with enalapril in Nigerian patients with congestive heart failure. Proceedings of the 17th Annual Scientific Meeting of the Nigerian Cardiac Society, Ibadan, Abstract No. 14, 1988;
Balogun M.O., Ajayi A.A. Ladipo G.O.A., Spectrum of exercise treadmill responses in normotension, essential hypertension and hypertensive heart failure. Proceedings of the 17th Annual Scienitic Meeting of the Nigerian Cardiac Society. Ibadan, Abstract No. 17, 1988;
Ajayi A.A., Enalaprilat concentration effect modeling. 1st Intenational Symposium on Heart Failure. Mechanisms and Management, Jerusalem, Israel. Abstract Poster 109, 1989;
– Ajayi A.A., Balogun M.O. and Ladipo G.O.A., Possible Mechanisms of ACE-inhibitors reduction of sudden cardiac death. 18th Annual Scientific Meeting of Nigerian Cardiac Society, Lagos. Abstract No. 5, 1989;
– Ajayi A.A. and Ukponmwan O.E., Angiotensin system modulates novelty induced rearing in rats. Proceedings- West African of Pharmacology, 030, Port Harcourt, Nigeria, 1989;
– Ajayi A.A. Akinsola A., Ogunrin O. and Adegbulugbe S.A., Enalapril with standard therapy in resistant hypertension and chronic renal failure in Nigerians. Proceedings of 2nd Nigerian Association of Nephrology Conference, Lagos, Nigeria, P. 12, 1989;
– Ajayi A.A. and Ukponmwan O.E., Evidence of angiotensin-II modulation of novelty induced rearing in the rat. European Journal Pharmacology, 183, 504-5, 1990;
– Ajayi A.A. and Balogun M.O., Inhibition of angiotensin converting enzyme in heart failure in Nigerians. 19th AGM and Scientific Conference, West African Society for Pharamcology. Lagos, P.4., 1990;
– Ajayi A.A., Oyewo E.A., Balogun M.O., The clinical pharmacology of enalapril. Scientific Conference in honor of Professor T.A.I. Grillo O.A.U. Ile-Ife. CS.4. (Feschcrift), 1990;
– Ajayi A.T., Balogun M.O., Ajayi A.a, Chest X-ray and echocardiopgraphy prediction of self-paced exercise to tolerance on myocardial oxygen consumption in heart failure. Scientific Conference in honor of Professor T.A.I. Grillo, Ile-Ife, CS. 11. (Feschcrift), 1990;
– Ajayi A.A., Balogun J.A., Symptom-limited, self-paced walking in the functional capacity evaluation in cardiovascular disease. 20th Annual Scientific Conference of Nigerian Cardiac Society, Benin, 1991, Abstract No. 8p, 1991;
– Babalola R.O., Ajayi A.A., Haemodynamic study on hypertensive diabetic Nigerians. 20th Annual Scientific Conference of Nigerian cardiac Society. Benin, 1991. Abstract No 8p, 1991;
– Babalola R.O., Ajayi A.A., Haemodynamic study on hypertensive diabetic Nigerians. 20th Annual Scientific Conference of Nigerian cardiac Society. Benin, 1991. Abstract No 8p, 1991;
– Akinwusi O. Ajayi A.A., Haemodynamic spectrum of hypertensive heart disease in Nigerians. . 20th Annual Scientific Conference of Nigerian cardiac Society. Benin, 1991. Abstract No 3p, 1991;
– Babalola R.O. Ajayi A.A., Oyelola O.O., Target organ damage and hyperlipidaemia in hypertensive-diabetic Africans. Third International Symposium on Hypertension Associated with Diabetes Mellitus, Boston MA, USA. Abstract N. 110, 1991;
– Ajayi A.A., Raji M.A. Akintomide A.O., Babalola R.O., The cardiovascular effects of the concurrent administration of ACE inhibitor, calcium antagonist and adrenergic antagonist in healthy Africans, BPS Proceedings, Newcastle, April 1992. British Journal of Clinical Pharmacology. 34, 17p, 1992;
– Ajayi A.A., Copper J.A., Rubin P.C., Horn E.H., Effects of unfractionated heparin and the low molecular weight heparins, dalterparin and enoxaprin on platelet behavior in pregnancy. 24th International Society of Hematology Congress, London Sept. 1992. Abstract No. 347A, 1993;
– Ajayi A.A. Cooper JA, Horn EH , Rubin PC. The effects of unfractionated heparin and the low molecular weight heparins, dalterparin and enoxaprin on platelet behavior in pregnancy. British Journal of Clinical Pharmacology 35, 90-91P, 1993;
– Ajayi A.A. Mathur R. Halushka P.V., Testosterone increase human platelet thromboxane A2 receptor density. Clinical Research , 42(2), 252A, 1994;
– Halushka P.V., Ajayi A.A., Mathur R., Testosterone increase human platelet TXA2 receptor density. 9th International Conference on prostaglandins and related compounds. Florence, Italy, June 6-10, P.28, 1994;
– Halushka P.V., Ajayi A.A., Schror K, Matsuda K. Masuda A., Mathur R., Cardiovascular TXA2 receptor regulation by sex steroids. Mediators in cardiovascular system. International Conference, June 2-5. Malta, 1994;
– Ajayi A.A., Halushka P.V., Cardiovascular thrombogenicity of testosterone. 24th Annual Conference of Nigerian Cardiac Society, Ile-Ife, 1995. Abstract No.3, p.14, 1995;
– Ajayi AA, Halushka PV. Testosterone increases platelet thromboxane A2 receptors and aggregation responses : implications for thrombotic cardiovascular diseases. Association of Physicians of Nigeria National Conference, Lagos, March 1995;
– Adewole A.D., Ikem R.T., Adigun A.Q., Akintomide A.O., Balogun M.O., Ajayi A.A.: A 3 year study of the impact of ACE inhibitors on the prognosis of congestive heart failure in Nigerians. Proceedings of 24th Annual Conference of Nigerian Cardiac Society, Ile-Ife, 1995;
– Adigun A.Q., Akintomide A.O., Balogun M.O., Ajayi A.A.: An echocardiographic and clinical audit of rheumatic heart disease. 24th Annual Conference of Nigerian Cardiac Society, Ile-Ife, 1995;
– Afolabi M.A., Ajayi A.A., Balogun M.O., Akintomide A.O., Ajayi O.E.: Oral therapy with ACE inhibitor, Alpha 1 antagonist and Thiazide diuretic combination, normalizes BP in hypertensive crises. Proceedings of 24th Annual Conference of Nigerian Cardiac Society, Ile-Ife, 1995;
– Ajayi A.A.: ‘ACE inhibition’: From molecular Pharmacology to man “State-of-the-art-lecture.” 24th Scientific Conference of Nigerian Cardiac Society, Ile-Ife, April 1995;
– Adigun A.Q., Akintomide A.O., Balogun M.O., Ajayi A.A.: An echocardiographic and clinical audit of rheumatic heart disease. Abstract 1. Proceedings of Nigerian Cardiac Society 24th Annual Conference Ile-Ife, P.13, 1995;
– Afolabi M.A., Ajayi A.A., Balogun M.O., Akintomide A.O., Ajayi O.E., Oral therapy with ACE inhibitor, Alpha 1 blocker and thiazide diuretic combination normalizes BP in hypertensive crises. Proceedings of 24th Annual Conference of Nigerian Cardiac Society, Ile-Ife. Abstract 6, P 16, 1995;
– Balogun M.O., Ikem R.T., Akintomide A.O., Ajayi A.A., Determinants of intra-hospital mortality in Nigerian patients with congestive heart failure. Proceedings of 24th Annual Conference of Nigerian Cardiac Society, Ile-Ife. Abstract 8, P 18, 1995;
– Adewole A.D., Ikem R.T., Adigun A.Q., Akintomide A.O., Balogun M.O., Ajayi A.A.: A 3 year clinical review of the impact of ACE inhibitors on the prognosis of congestive heart failure in Nigerians. Proceedings of 24th Annual Conference of Nigerian Cardiac Society, Ile-Ife, Abstract 10, P.20, 1995;
– Balogun M.O., Akintomide A.O., Ajayi O.E., Ajayi A.A., An Open Non-comparative study to examine the antihypertensive effect of a fixed dose of combination of Lisinopril (20mg) plus hydrochlorothiazide (12.5 mg) (Zestoretic) in patients with mild to moderate essential hypertension. 24th Annual Scientific Conference of Nigerian Cardiac Society, Ile-Ife, 1995. Abstract 12, P.20, 1995;
– Ajayi A.A., Babalola R.O. Oyelola O.O., Stein R.: Hypertensive-Diabetic Nigerian patients: Echocardiography, Treadmill exercise tolerance, Lipid profile and therapeutic studies. 2nd Nigerian Society of Hypertension meeting, Ibadan, Nigeria, Abst 8, 1995;
– Ajayi AA, Afolabi MA, Balogun MO et al., Angiotensin converting enzyme inhibitor- thiazide diuretic- alpha-1 blocker combination normalizes blood pressure in hypertensive crises. 2nd Nigerian Society of Hypertension meeting, Ibadan, Abstract 2, 1995;
– Sofowora G., Ajayi A.A. Balogun M.O. et al., Concurrent Alpha 1 blockade and ACE inhibition in congestive heart failure. 20th A G M and Scientific Meeting, West African College of Physicians. Lagos , November 1995;
– Ajayi A.A., “Hypertension in Nigerians”- An Update. Nigerian Medical Association/Pfizer plc, Akure, Ondo State, October 12, 1995;
– Ajayi A.A. Balogun M.O., Sofowora G.G.: Concurrent Alpha 1 adrenergic blockade and ACE inhibition in the treatment of congestive heart failure. 4th International Symposium on heart failure, Jerusalem, Israel, Eur Jorunal of Heart Failure. Abstract No, 1736, 1996;
– Rotimi O, Ajayi A.A., Odesanmi W.O., Pathological basis of sudden cardiac death in Nigerians, Nigerian Cardiac Society Silver Jubilee scientific conference Lagos, Abstract 1, 1996;
– Kolawole B.A., Ajayi A.A., Prognostic indices for intrahospital mortality in Hypertensive Diabetic Nigerians. Proceedings to Silver Jubilee meeting for the Nigerian Cardiac Society, Lagos, 1996;
– Adigun A.Q., Ajayi A.A., ACE inhibition induced cough in Nigerians. Nigerian Cardiac Society Silver Jubilee scientific conference. Lagos, P 24, 1996;
– Sofowora G.G., Adigun A.Q., Ajayi A.T., Ajayi A.A., Evidence of synergism between ACE-inhibitors and Alpha 1 Adrenergic blockade during forearm isometric exercise in normal man. Proceeding Nigerian Cardiac Society Lagos, 1996;
– Adebayo R.A., Sofowora G.G., Onayemi O., Ajayi A.A., Udoh S.J., Efficacy and Safety of niacin, predisolone and combination in chloroquine-induced pruritus in malaria fever: Comparison with antihistamines. Proceedings of the West African College of Physicians (Nigeria Chapter) Conference, Ile-Ife, November 1997;
– Ajayi A.A. Akintomide AO, Sofowora G, Adigun A.Q, Balogun M.O. Haastrup A.T., Concurrent Renin Angiotensin inhibition and Alpha 1 adrenergic blockade with diuresis as Rational therapy of cardiovascular disease. Proc. 5th Annual Scientific and General meeting Nigerian Society of Hypertension P12. Lagos, 1997;
– Ajayi AA, Balogun MO, Akintomide AO, Andy JJ, Chukwuani CM., A double –blind , placebo controlled , randomized parallel group study of the antihypertensive efficacy and safety of cilazapril, hydrochlorothiazide and their combination in Nigerians with mild-to moderate essential hypertension. Proceedings of the 5th annual conference of the Nigerian Hypertension Society, P 12-13, Lagos 1997;
– Adigun AQ, Ajayi AA., Angiotensin converting enzyme induced cough. Proceedings of the Annual West African College of Physicians (Nigeria Chapter) Ile-Ife, 1997;
– Adebayo RA , Sofowora GG, Udoh SJ, Onayemi O, Ajayi AA., Efficacy and safety of Niacin , prednisolone , and combination in chloroquine-induced pruritus in malaria fever: comparison with anti-histamines. Proceedings of the West African College of Physicians( Nigeria Chapter) conference, Ile-Ife, November, 1997;
– Adigun AQ, Sofowora GG, Ajayi AA., Adjunctive sympathoplegic therapy in congestive heart failure: alpha or beta blockade ? Proceedings of the 27th annual conference of the Nigerian Cardiac society. Ilorin , Abstract no 4, December 7-8. 1998;
– Ajayi AA , Adigun AQ, Ajayi OE, Sofowora GG., Combined captopril –prazosin versus isosorbide dinitrate – hydralazine in acute left ventricular failure. A comparison of impact on cardiorespiratory function and survival. 27th annual conference of the Nigerian cardiac society. Ilorin, abstract no3, 1998;
– Kolawole BA, Ajayi AA., Prognostic Indices for in-hospital mortality of hypertensive-diabetic Nigerians. International Diabetes Federation Conference, Osaka , Japan, 1998;
– Adigun AQ, Ishola DA, Akintomide AO, Ajayi AA., Trends in the prescription patterns of antihypertensive drugs in Nigerian patients with essential hypertension. Nigerian Society of Hypertension annual scientific conference, Lagos, 2000;
– Ajayi AA, Adigun AQ, Asiyanbola B. Cardiac autonomic function in Nigerians with congestive heart failure. RCMI international symposium on Health disparities. Puerto Rico. November, 2000;
– Ajayi AA, Adigun AQ, Sofowora GG., Adjunctive sympathoplegic therapy to ACE –inhibition in blacks with congestive heart failure : alpha or beta blockade ? Clinical Pharmacology & Therapeutics, 69 p 4. 102nd ASCPT conference Florida, USA, 2001;
– Ajayi AA, Pamugo J, Hercule HC, Oyekan AO., Interactions between the renin-angiotensin system and the alpha-1 adrenergic system on systemic and renal hemodynamics in healthy and acute renal failure rats : role of nitric oxide. Experimental Biology meeting, Abstract 202.7, Florida, March 2001;
– Hercule HC, Ajayi AA, Oyekan AO., Role of endothelin –1 in U46619 induced increase in renal medullary blood flow. Experimental biology meeting,60, Florida March 2001;
– Ajayi AA, Hercule HC, Hayes BE, Oyekan AO., Gender differences in the vascular and platelet reactivity toTXA2 mimetic and to endothelial nitric oxide system in Zucker fatty diabetic rats. Experimental Biology scientific conference, abstract 694.12, New Orleans, Louisiana , 2002;
– Ajayi AA, Adigun AQ, Ishola DA , Akintomide AO., Real world therapeutic efficacy of old and new antihypertensive drugs in Nigerians. International Society of Hypertension in Blacks, Orlando Florida, 2002, abstract no 2. J Natl Med Assoc., 94, 278, 2002;
– Mutembei L, Ogungbade O, Ajayi AA., Endothelin receptor subtype and TXA2 mimetic interactions in Zucker Diabetic rats : role of sex hormones? Annual Biomedical and Pharmaceutical research conference , New Orleans, LA ,Nov 13, 2002;
– Ajayi AA, Ogungbade O., Sex hormones and Endothelin-1- TXA2 in Zucker diabetic Rats . Experimental Biology meeting, Abstract 583, San-Diego, California, 2003; (Invited Symposium-American Society of Pharmacology and Experimental Therapeutics);
– Ajayi AA, Newaz MA, Hercule HC, Bode CO, Oyekan AO., Pausinystalia Yohimbie extract has endothelin / nitric oxide actions. Experimental Biology conference 2003. Abstract 591, San Diego California, 2003;
– Ajayi AA , Kolawole BA., Sickle cell trait is a risk factor for diabetic vascular complications in blacks. National Medical Association convention abstract. Philadelphia, PA, 2003;
– Kolawole BA, Ajayi AA, Ikem RT., Sickle cell trait and gender influence diabetic complications in Africans. Endocrinology Society UK, 195TH Scientific meeting, November 3-5, 2004;
– Ajayi AA, Kolawole BA., A double blind comparison of naltrexone and promethazine in patients with an established history of severe chloroquine-induced pruritus n malaria fever. Clin Pharmacol Ther, 75 (2) p 25, 2004;
– Ajayi AA, Halushka PV., Castration reduces human platelet TXA2 receptor density and aggregability. Clin Pharmacol Ther, 77 (2). p 43, 2005;
– Ajayi AA, Halushka PV., Castration reduces human platelet TXA2 receptor density and aggregability. Clin Pharmacol Ther, 77 (2). p 43, 2005;
– Ajayi AA, Fidelis P. Flutamide regulates microcirculation in female Zucker diabetic rats 6th Diabetic Technology Society conference, Atlanta, November 2-6, 2006;
– Ajayi AA, Abiona TC, Ajayi OE., Does pre-existing or early onset valvular regurgitation accelerate hypertensive heart disease in blacks ? 62nd Annual Scientific Meeting of the High Blood Pressure Council of the American Heart Association. LB062, Atlanta, September 19, 2008;
– Is valvular regurgitation a risk factor for arrhythmogenicity in hypertensive heart disease and failure ? : Studies with Doppler echocardiography and 24 hour Holter EKG monitor. 51ST IsraelHeart Society Conference, Jerusalem, April 2012;
– Ajayi AA, Akintomide AO, Ajayi OE., Valvular Regurgitation may increase risk of arrhythmias in hypertensive heart failure in blacks. 66th meeting of the High Blood Pressure Research Council Meeting of the American Heart Association. Hypertension 2012. 60:A326, Abstract 309. Washington DC, September 19-22;
– Olamoyegun M, Kolawole BA, Ajayi Adesuyi., A study of the influence of West African ethnicity and gender on Beta-cell function and insulin sensitivity in essential hypertensives treated with hydrochlorothiazide, and hydrochlorothiazide-lisinopril combination. Society for Endocrinology, BES Endocrine Abstracts (2015)38. P265. Edinburgh UK, November 2, 2015.
OTHER PUBLICATIONS ON OR ABOUT ME OR MY RESEARCH WORK. PRE –ALTIMETRIC – WIDER IMPACTS
– 91, 2694-98 “of muscle, mice, and men” Editorial om our research published in the journal Circulation, Circulation 1995;
– Cure for Hypertension – Editorial written in recognition of my groups research work with synergistic combination of drugs including ACEI-Inhibitors and sympathoplegics to reduce mortality by 50% in black patients with congestive heart failure and acute pulmonary edema, and in hypertensive type -2 diabetic patient, Guardian Nigeria Editorial of March 18, 1997;
– Report of the discovery by our research of the involvement of opiate receptors and non –histaminergic mechanisms of the then enigmatic severe itching due to chloroquine, Agence France Press, September 13, 1999;
– Cachexia is a world wide problem –Editorial on work on Cachexia, International Journal of Cardiology, 2001;
– Review of my book “Diaspora Medicine” Several others in Nigerian News papers, Houston Punch, Chicago Inquirer, Google+, Mendeley, Journal of National Medical Association Book Review, 2002.
GRADUATE SUPERVISION –THESIS/DISSERTATIONS
M.SC . PROGRAMS
– Isi James , MSc. ( Physiotherapy ) “Cardiovascular responses to inversion of the head”;
– Oyeyemi Younous. MSc. ( Physiotherapy ). “ The effect of aerobic training on the cardiovascular responses to head-down posture “;
– Pungong JI . MSc. ( Physiology ) “ Effects of exercise intensity on the cardiorespiratory responses of atheletes and non-atheletes in Nigeria”;
FELLOWSHIP DISSERTATION SUPERVISED
– Dr R.O. Babalola, Fellowship of West African College of Physicians Dissertation.“ The Effect of Hypertension on the microvascular complications of Diabetes Mellitus “,1992. (Recipient of a Joslin Diabetes Center Travel Fellowship Award, Harvard Medical School Boston MA, November 1991);
– Dr PO Akinwusi – Fellowship of the West African College of Physician Dissertation. “The spectrum of hypertensive heart disease in Nigerians : A correlative study of echocardiography , treadmill exercise performance and cardiovascular autonomic function”,1993;
– Dr GG Sofowora- FWACP dissertation. “The effect of concurrent α-1 or β-1 adrenergic blockade and ACE inhibition in the treatment congestive heart failure in Nigerians.” (Recipient of a Merck, Sharp and Dohme international Fellowship in clinical pharmacology (In Preparation),1997;
– Dr RT Ikem., Fellowship of the Medical College of Physic of Nigeria Dissertation“ Renal function and proteinuria in Nigerians with Diabetic nephropathy ”1998;
– Dr SO Olateju. Fellowship of the Medical College of ophthalmologists of Nigeria. “The ocular hypotensive effect of selective ( betaxolol) and non-selective
( timolol) beta-adrenergic blockers in healthy Nigerians and glaucoma patients ”, 1998;
– Dr AQ Adigun. –Fellowship of the West African College of Physicians ( FWACP).”Cardiac autonomic function in Nigerians with chronic congestive heart failure “, 1998. (Recipient of a Merck, Sharp and Dohme International Fellowship in clinical pharmacology, 2000);
SUMMER RESEARCH INTERNS
– Deandra Dixon. Pharm .D, Published work, 2001;
– James Cory Pharm.D, Published work, (3rd Place in Research Presentation of work at National Association of Minority Pharmacy Students Conference), 2002;
– Lucy Mutembei Pharm .D, Published work. (1st and 3rd place winners in National Research Conferences of Minority Pharmacy Researchers), 2003;
HOBBIES:
– Birdwatching
– Classical music
– Computer games
SOCIAL CLUBS:
– Klub 2, University of Ife, 1977;
– Staff Club, Obafemi Awolowo University, Ile-Ife.
SYNERGISTIC AND MISCELLANEOUS ACTIVITIES:
ACADEMIC PRIZES DONATED:
– Dr Edward Adefemi Oyewo Prize (in conjuction with Pfizer Nigeria PLC) – For the best student in the Clinical pharmacology course at the Faculty of Pharmacy, Obafemi Awolowo University, Ile Ife, Nigeria, 1996;
– Adeline and Alex Olu Ajayi Prize – For the best student in Physiology at the Obafemi Awolowo University Medical School, ile-Ife, Nigeria, 1997;
– Grillo-Durotoye Prize – For excellent, novel and significant research publication in the biomedical and clinical sciences or public health by Faculty at the Obafemi Awolowo University, Ile-Ife, 2001; Scholarship inaugurated and awarded continually -Trustee
– The Adeline Olu Ajayi University Scholarship for children of Police officers- Lagos Police Command Area – Surulere/Bode Thomas, Lagos state, since 2007.
SCIENTIFIC CONFERENCES ORGANIZED / PART OF ORGANIZING COMMITTEE:
– Coordinator, Feschcrift for Prof TAI Grillo, with posters and oral presentations –Obafemi Awolowo University Conference Center, Ile-ife, Osun State, 1990;
– West African College of Physicians (Nigerian Chapter) Scientific Conference and Annual General Meeting 1990, 1991;
– Judge of Donated Prizes from Pfizer and Sandoz for young researchers at the Nigerian Cardiac Society conferences.
– Coordinator, Scientific seminars, College of Health Sciences, University of Ife, 1989-1991;
– Nigerian Cardiac Society, 24th Annual Scientific Conference and General Meeting, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, Nigeria . In charge of Abstract review acceptance, 1994;
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“Please send your updated CV to: [email protected]” – Editor
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